Founder and Executive Director, Vitamin C Institute for Clinical Integration (VCICI)
Lior Sher, JD, is the Founder and Executive Director of the Vitamin C Institute for Clinical

Integration (VCICI), a global nonprofit advancing the science, clinical application, and

translational education of high-dose Vitamin C Therapy (VCT). A thought leader in redox

medicine and integrative clinical strategy, she has redefined Vitamin C as a cornerstone

intervention in cancer, chronic illness, complex infections, and immune dysregulation.

She is the author of The C Word: Conspiracy, Cover-Up, and Controversy—The Forbidden

Cures from Cancer to COVID and Beyond, a scientific exposé uncovering suppressed clinical

data and the untapped therapeutic potential of Vitamin C. The book challenges conventional

medicine’s neglect of ascorbate and offers clinicians and patients a rigorous investigation into

one of the most underutilized molecules in modern medicine.

With a multidisciplinary background spanning biotechnology, healthcare innovation, and law,

Lior is a patented biomedical inventor, educator, and internationally recognized speaker known

for translating molecular science into evidence-based, systems-oriented therapeutics. Through

VCICI, she directs the Institute’s Certification Program and the annual C-MPOSIUM, a CME/CE-

accredited global conference.

Her educational framework emphasizes redox-targeted strategies for endocrine recalibration,

immune modulation, mitochondrial repair, and systemic recovery—applied across diverse

specialties including oncology, regenerative medicine, biological dentistry, and holistic

veterinary care.

Lecture Title: Ascorbate at the Core of Clinical Medicine: Redox Modulator, Recovery

Driver, and Regenerative Catalyst

Advancing Mitochondrial Health, Hormonal Optimization, and Therapeutic Synergy in Oncology,

Infection, and Precision Regenerative Therapies

Abstract

Ascorbate—the physiologically active form of Vitamin C—serves as a cornerstone of redox

regulation and clinical recovery. More than a micronutrient, ascorbate operates as a redox-

active cofactor essential to hormone biosynthesis, mitochondrial energy production, immune

recalibration, collagen dynamics, and neurotransmitter balance. Its activity positions it as a

systems-level integrator rather than a peripheral adjunct.

This session examines recent scientific advances and clinical translation, highlighting how

ascorbate governs redox signaling, accelerates tissue repair, and enhances therapeutic synergy

across endocrine, neurologic, metabolic, and immune networks. Special focus will be given to

the role of chronic oxidative stress and marginal ascorbate insufficiency in undermining recovery

from trauma, chronic infection, degenerative disease, and age-related decline.

Clinicians will gain insight into strategies for sustaining physiologic ascorbate

concentrations—an approach that stabilizes redox balance, conditions the biological terrain, and

optimizes the attainment of Peak Plasma Concentrations (PPC) during IV therapy. Such terrain

readiness not only broadens the therapeutic window for selective cytotoxicity in oncology and

infectious disease but also improves outcomes in regenerative interventions, surgical recovery,

hormone optimization, and bio-oxidative modalities such as ozone.

By preserving mitochondrial integrity, coordinating immune responses, and driving extracellular

matrix repair, ascorbate emerges as an indispensable catalyst for redox recalibration and

systemic resilience. Delivered through sodium-dependent SVCT transporters, sodium ascorbate

offers enhanced tolerability and intracellular uptake, making it the preferred form for patients

with high oxidative burden and complex clinical needs.

Learning Objectives

At the conclusion of this session, participants will be able to:

1. Explain how ascorbate functions as a redox-active cofactor governing mitochondrial

energetics, immune modulation, collagen remodeling, and hormone synthesis.

2. Identify the clinical implications of chronic oxidative stress and suboptimal ascorbate

status in trauma, immune dysregulation, and degenerative disease.

3. Discuss how optimizing physiologic ascorbate levels potentiates therapeutic synergy

across integrative, conventional, and regenerative approaches.

4. Incorporate evidence-based strategies for daily and intravenous ascorbate delivery to

improve terrain readiness, systemic recovery, and long-term clinical outcomes.