1953 Efficacy and safety of vital bleaching in teenagers using 6.5% hydrogen peroxide strips during the day or 10% carbamide peroxide tray system overnight

K.J. DONLY1 , F. GARCIA-GODOY2 , A. SEGURA1 , L. BAHARLOO1 , E. ROJAS-CANDELAS1 , X. ZHOU3 , and R.W. GERLACH3 , 1 University of Texas Health Science Center--San Antonio, USA, 2 Tufts University, Boston, MA, USA, 3 The Procter & Gamble Company, Mason, OH, USA

Objective: The purpose of the study was to compare a 6.5% hydrogen peroxide impregnated polyethylene strip tooth whitening system to a standard 10% carbamide peroxide tooth whitening system utilized overnight in a nightguard tray delivery system.

Methods: One hundred and six subjects 11 to 18 years of age (mean 14.7 years) were recruited to participate in this randomized clinical trial. The study population included 61 females and 45 males. Treatment groups were balanced with respect to demographic characteristics and baseline tooth color. Thirty-five subjects used a 10% carbamide peroxide gel, delivered overnight in a nightguard tray. Seventy-one subjects used a 6.5% hydrogen peroxide whitening strip for 30 minutes twice per day.

Results: Digital images were obtained at baseline, and again, after two and four weeks treatment, and outcomes were measured in terms of CIE units, where DL* indicates lightness, Db* indicates yellowness and DE* represent composite color.

Conclusion: Results demonstrated both tooth whitening systems significantly whitened teeth (p<0.0001). Both systems were well tolerated, and most events were mild in severity following the instructed use of the two systems. (This research was supported, in part, by The Procter & Gamble Co.)

Seq #185 - Clinical Evaluations of Tooth Bleaching and Sensitivity 11:00 AM-12:15 PM, Friday, 8 March 2002 San Diego Convention Center Exhibit Hall C